The premiere of La cambiale di matrimonio at the ROF was on August 19th, 1991 at the Auditorium Pedrotti. Donato Renzetti conducted the RAI Symphony Orchestra of Turin and a cast consisting of Enzo Dara (Tobia Mill), Soeun Jeun (Fannì), Luca Canonici (Edoardo Milfort), Roberto Frontali (Slook), Stefano Rinaldi Miliani (Norton) and Marilena Laurenza (Clarina). The production was staged by Luigi Squarzina, with sets and costumes by Giovanni Agostinucci.
The staging was revived on two occasions. In 1995, with Yves Abel on the podium of the ORT-Orchestra della Toscana. In the singing company, Bruno Praticò (Tobia Mill), Eva Mei (Fannì), Edoardo Milfort (Bruce Fowler), Roberto Frontali (Slook), Stefano Rinaldi Miliani (Norton), Alessandra Palomba (Clarina). In 2006, in the space of the then BPA Palas (now Vitrifrigo Arena), Umberto Benedetti Michelangeli conducted the Haydn Orchestra of Bolzano and Trento. The cast included Paolo Bordogna (Tobia Mill), Désirée Rancatore (Fannì), Saimir Pirgu (Edoardo Milfort), Fabio Maria Capitanucci (Slook), Enrico Maria Mirabelli (Norton) and Maria Gortsevskaya (Clarina).
A new production was offered on March 1st , 2019, as part of Rossini's birthday celebrations, in collaboration with the Pesaro Conservatory and the Teatro Lirico di Cagliari. Alessandro Bonato conducted the Conservatory Orchestra and a cast that included Nicolò Donini (Tobia Mill), Claudia Muschio (Fannì), Anatolii Pogrebnyi (Edoardo Milfort), Carles Pahon (Slook), Sergei Morozov (Norton), and Mariangela Marini (Clarina). The staging, directed by Francesco Calcagnini and Davide Riboli, was produced by the Academy of Fine Arts of Urbino.
The most recent edition of the opera, co-produced with the Royal Opera House Muscat, was staged during the ROF 2020 edition at Teatro Rossini. Dmitry Korchak conducted the Orchestra Sinfonica G. Rossini. In the singing company were Carlo Lepore (Tobia Mill), Giuliana Gianfaldoni (Fannì), Davide Giusti (Edoardo Milfort), Iurii Samoilov (Slook), Pablo Galvez (Norton), and Martiniana Antonie (Clarina). Direction was by Laurence Dale, with sets and costumes by Gary McCann.